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Literature summary for 1.14.14.18 extracted from

  • Akram, M.; Syed, A.S.; Kim, K.A.; Lee, J.S.; Chang, S.Y.; Kim, C.Y.; Bae, O.N.
    Heme oxygenase 1-mediated novel anti-inflammatory activities of Salvia plebeia and its active components (2015), J. Ethnopharmacol., 174, 322-330.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoheme + [reduced NADPH-hemoprotein reductase] + O2 Mus musculus
-
biliverdin + Fe2+ + CO + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
RAW-264.7 cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protoheme + [reduced NADPH-hemoprotein reductase] + O2
-
Mus musculus biliverdin + Fe2+ + CO + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
Mus musculus
HO-1
-
Mus musculus

Expression

Organism Comment Expression
Mus musculus cell treatment with Salvia plebeia methanolic extract significantly induces the expression of hemeoxygenase-1 up