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Literature summary for 1.14.14.18 extracted from

  • Badyal, S.K.; Eaton, G.; Mistry, S.; Pipirou, Z.; Basran, J.; Metcalfe, C.L.; Gumiero, A.; Handa, S.; Moody, P.C.; Raven, E.L.
    Evidence for heme oxygenase activity in a heme peroxidase (2009), Biochemistry, 48, 4738-4746.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information a variant of ascorbate peroxidase, W41A, which reacts slowly with tert-butyl hydroperoxide does not form the usual peroxidase compound I intermediate, but instead forms a product in which the heme is cleaved at the alpha-meso position, analogous to the heme oxygenase mechanism Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P09601
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + electron donor + O2
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Homo sapiens biliverdin + Fe2+ + CO + oxidized electron donor + H2O
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