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Literature summary for 1.14.14.18 extracted from
- Heme oxygenase enzyme activity in human seminal plasma of fertile and infertile males (2008), Andrologia, 40, 292-297.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | positive correlation between seminal plasma HO enzyme activity and sperm concentration, sperm motility percentage, motile spermatozoa ml-1 and sperm normal morphology per cent | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seminal plasma | activity is very low in obstructive azoospermia specimens, low in nonobstructive azoospermia, moderate in oligozoospermia while higher in normozoospermia. HO-2 expression in all studied groups whereas HO-1 is highly expressed in fertile normozoospermic group compared with other groups | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| heme + electron donor + O2 | - |
Homo sapiens | biliverdin + Fe2+ + CO + oxidized electron donor + H2O | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| heme oxygenase | - |
Homo sapiens |
| HO-1 | - |
Homo sapiens |
| HO-2 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | HO enzyme activity in the human seminal plasma is related to spermatogenesis and sperm-motility processes | Homo sapiens |
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