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Literature summary for 1.14.14.17 extracted from

  • Gerpe, A.; Alvarez, G.; Benitez, D.; Boiani, L.; Quiroga, M.; Hernandez, P.; Sortino, M.; Zacchino, S.; Gonzalez, M.; Cerecetto, H.
    5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene (2009), Bioorg. Med. Chem., 17, 7500-7509.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-(3-phenyl-2-propenyl)piperazine-1-ylamide of 3-(2-furyl)propenoic acid analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-(3-phenyl-2-propenyl)piperazine-1-ylamide of 3-(5-nitro2-furyl)propenoic acid analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-(3-furyl-2-propenylidene)thiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-(5-nitrofurfurilydene)thiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-(5-nitrothenylidene)thiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-furfurylidenethiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-thenylidenethiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
4-allyl-1-[3-(5-nitro-2-furyl)-2-propenylidene] analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
N-(2-hydroxyethyl)-3-(5-nitro-2-furyl)propenamide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi
Thiosemicarbazide analysing effect on accumulation of more squalen and less (S)-squalene-2,3-epoxide in Trypanosoma cruzi. Analysing antifungal effect on Microsporum canis C 112, Epidermophyton floccosum C 114, Trichophyton rubrum C 110, Trichophyton mentagrophytes ATCC 9972 and Microsporum gypseum C 115 Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
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Synonyms

Synonyms Comment Organism
squalene epoxidase
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Trypanosoma cruzi