Cloned (Comment) | Organism |
---|---|
coexpression of HaG8H with the enzyme combination HaGAS1 + HaGAO in Nicotiana benthamiana leaves results in the formation of the lactonized version inunolide | Helianthus annuus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 | Helianthus annuus | - |
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helianthus annuus | F8S1H3 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Helianthus annuus | 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 | germacra-1(10),4,11(13)-trien-12-oate i.e. germacrene A acid | Helianthus annuus | 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP71BL1 | - |
Helianthus annuus |
GAA 8beta-hydroxylase | - |
Helianthus annuus |
HaG8H | - |
Helianthus annuus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P-450 | heme-thiolate protein | Helianthus annuus |