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Literature summary for 1.14.14.159 extracted from

  • Mafu, S.; Ding, Y.; Murphy, K.M.; Yaacoobi, O.; Addison, J.B.; Wang, Q.; Shen, Z.; Briggs, S.P.; Bohlmann, J.; Castro-Falcon, G.; Hughes, C.C.; Betsiashvili, M.; Huffaker, A.; Schmelz, E.A.; Zerbe, P.
    Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize (2018), Plant Physiol., 176, 2677-2690 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
15,16-epoxydolabrene + O2 + [reduced NADPH-hemoprotein reductase] Zea mays the enzyme is involved in biosynthesis of dolabralexin. It catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 3beta-hydroxy-15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?
dolabradiene + O2 + [reduced NADPH-hemoprotein reductase] Zea mays the enzyme is involved in biosynthesis of dolabralexin. It catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?

Organism

Organism UniProt Comment Textmining
Zea mays
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Zea mays
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
15,16-epoxydolabrene + O2 + [reduced NADPH-hemoprotein reductase] the enzyme is involved in biosynthesis of dolabralexin. It catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 Zea mays 3beta-hydroxy-15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?
15,16-epoxydolabrene + O2 + [reduced NADPH-hemoprotein reductase] the enzyme catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 Zea mays 3beta-hydroxy-15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?
dolabradiene + O2 + [reduced NADPH-hemoprotein reductase] the enzyme is involved in biosynthesis of dolabralexin. It catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 Zea mays 15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?
dolabradiene + O2 + [reduced NADPH-hemoprotein reductase] the enzyme catalyses the epoxidation of dolabradiene at C-16, followed by hydroxylation at C-3 Zea mays 15,16-epoxydolabrene + H2O + [oxidized NADPH-hemoprotein reductase]
-
?

Synonyms

Synonyms Comment Organism
CYP71Z16
-
Zea mays

Cofactor

Cofactor Comment Organism Structure
cytochrome P-450 a cytochrome P-450 (heme thiolate) enzyme Zea mays

Expression

Organism Comment Expression
Zea mays no increase of transcript level after inoculation with live spores of Fusarium verticillioides and Fusarium graminearum additional information
Zea mays increased transcript levels under abiotic stress condition (root treatments with 1 mM CuSO4) up

General Information

General Information Comment Organism
metabolism the enzyme is involved in biosynthesis of dolabralexin Zea mays