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Literature summary for 1.14.14.156 extracted from

  • Glawischnig, E.; Hansen, B.; Olsen, C.; Halkier, B.
    Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis (2004), Proc. Natl. Acad. Sci. USA, 101, 8245-8250.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
-
 Arabidopsis thaliana (E)-indol-3-ylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP79B2
-
 Arabidopsis thaliana
CYP79B3
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana the transcript level of CYP79B2, but not CYP79B3, is increased 3fold upon induction of camalexin by silver nitrate up

General Information

General Information Comment Organism
malfunction the cyp79B2/cyp79B3 double knockout mutant is devoid of camalexin, as it is also devoid of indole glucosinolates Arabidopsis thaliana
metabolism CYP79B2 plays an important role in camalexin biosynthesis Arabidopsis thaliana
physiological function only CYP79B2 and CYP79B3 contribute significantly to the indole-3-acetaldoxime pool from which camalexin and indole glucosinolates are synthesized Arabidopsis thaliana