Cloned (Comment) | Organism |
---|---|
cDNA, introduced into Aspergillus niger by transformation | Penicillium italicum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fungicides | - |
Penicillium italicum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57300 | - |
amino acid analysis | Penicillium italicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
eburicol + [reduced NADPH-hemoprotein reductase] + O2 | Penicillium italicum | - |
? + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Candida tropicalis | - |
- |
- |
Penicillium italicum | - |
filamentous fungal plant pathogen | - |
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
eburicol + O2 + [reduced NADPH-hemoprotein reductase] + O2 | - |
Penicillium italicum | 2-(3-hydroxy-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic acid + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
eburicol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Penicillium italicum | ? + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | lanosta-8,24-dien-3beta-ol | Saccharomyces cerevisiae | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | lanosta-8,24-dien-3beta-ol | Candida albicans | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | lanosta-8,24-dien-3beta-ol | Candida tropicalis | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | 4,4,14alpha-trimethyl-5alpha-cholesta-8,24-dien-3beta-ol | Saccharomyces cerevisiae | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | 4,4,14alpha-trimethyl-5alpha-cholesta-8,24-dien-3beta-ol | Candida albicans | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lanosterol + [reduced NADPH-hemoprotein reductase] + O2 | 4,4,14alpha-trimethyl-5alpha-cholesta-8,24-dien-3beta-ol | Candida tropicalis | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Saccharomyces cerevisiae | |
cytochrome P450 | - |
Candida albicans | |
cytochrome P450 | - |
Candida tropicalis | |
cytochrome P450 | - |
Penicillium italicum | |
heme | heme-thiolate enzyme | Saccharomyces cerevisiae | |
heme | heme-thiolate enzyme | Candida albicans | |
heme | heme-thiolate enzyme | Candida tropicalis | |
heme | heme-thiolate enzyme | Penicillium italicum |