Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ancymidol | dose-dependent inhibition with more than 80% by 0.075 mM ancymidol | Nicotiana tabacum | |
ketoconazole | dose-dependent inhibition with 95% inhibition at 0.1 mM ketoconazole | Nicotiana tabacum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Nicotiana tabacum | Q94FM7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-epiaristolochene + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | - |
Nicotiana tabacum | capsidiol + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5-epi-aristolochene-1,3-dihydroxylase | - |
Nicotiana tabacum |
5EAH | - |
Nicotiana tabacum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Nicotiana tabacum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.025 | - |
pH and temperature not specified in the publication | Nicotiana tabacum | ketoconazole | |
0.025 | - |
pH and temperature not specified in the publication | Nicotiana tabacum | Ancymidol |
Organism | Comment | Expression |
---|---|---|
Nicotiana tabacum | after an apparent lag phase of 8 h, a rapid induction of hydroxylase activity is observed 10 to 15 h after elicitor addition (cellulase or paraciticein) to the cell cultures, reaching a maximum by 18 h followed by a rather gradual decline of 10 to 20% over the next 8 h | up |