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Literature summary for 1.14.14.139 extracted from

  • Abrahamsson, A.; Gafvels, M.; Reihner, E.; Bjoerkhem, I.; Einarsson, C.; Eggertsen, G.
    Polymorphism in the coding part of the sterol 12alpha-hydroxylase gene does not explain the marked differences in the ratio of cholic acid and chenodeoxycholic acid in human bile (2005), Scand. J. Clin. Lab. Invest., 65, 595-600.
    View publication on PubMed
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Protein Variants

Protein Variants Comment Organism
additional information screening for genetic polymorphisms of gene CYP8B1, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesterol + [reduced NADPH-hemoprotein reductase] + O2 Homo sapiens
-
 12-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information Homo sapiens variation in the ratio between cholic acid and chenodeoxycholic acid in human bile are not due to polymorphisms in gene CYP8B1, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesterol + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 12-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information variation in the ratio between cholic acid and chenodeoxycholic acid in human bile are not due to polymorphisms in gene CYP8B1, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CYP8B1
-
 Homo sapiens
sterol 12alpha-hydroxylase
-
 Homo sapiens