Cloned (Comment) | Organism |
---|---|
gene CYP15A1, RT-PCR enzyme expression analysis | Blattella germanica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 | Blattella germanica | - |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Blattella germanica | D6CJJ9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
corpus allatum | - |
Blattella germanica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Blattella germanica | juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP15A1 | - |
Blattella germanica |
CYP15A1 protein | - |
Blattella germanica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Blattella germanica | |
NADPH-hemoprotein reductase | A flavoprotein containing both FMN and FAD. This enzyme catalyses the transfer of electrons from NADPH, an obligatory two-electron donor, to microsomal P-450 monooxygenases, EC 1.14.14._ | Blattella germanica |
Organism | Comment | Expression |
---|---|---|
Blattella germanica | starving reduces the enzyme expression | down |
General Information | Comment | Organism |
---|---|---|
malfunction | BgInR knockdown leads to a severe inhibition of juvenile hormone synthesis in adult female corpora allata, with a concomitant reduction of mRNA levels corresponding to 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase-1, HMG-CoA synthase-2, HMG-CoA reductase and methyl farnesoate epoxidase, phenotype, overview | Blattella germanica |
metabolism | the enzyme is important in the biosynthesis and regulation of juvenile hormone in the JH specific pathway | Blattella germanica |