Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.113 extracted from

  • Okamoto, S.; Yu, F.; Harada, H.; Okajima, T.; Hattan, J.; Misawa, N.; Utsumi, R.
    A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet (2011), FEBS J., 278, 2892-2900.
    View publication on PubMed
Search for more literature for 1.14.14.113

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ cytochrome P450 enzyme Zingiber zerumbet

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-humulene + O2 + [reduced NADPH-hemoprotein reductase] Zingiber zerumbet
-
 10-hydroxy-alpha-humulene + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Zingiber zerumbet
-
 gene CYP71BA1
-

Source Tissue

Source Tissue Comment Organism Textmining
rhizome transcripts of ZSS1 and CYP71BA1 encoding the two upstream enzymes of zerumbone biosynthesis are almost exclusively accumulated in rhizomes Zingiber zerumbet
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-humulene + O2 + [reduced NADPH-hemoprotein reductase]
-
 Zingiber zerumbet 10-hydroxy-alpha-humulene + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
alpha-humulene-8-hydoxylase
-
 Zingiber zerumbet
CYP71BA1
-
 Zingiber zerumbet

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Zingiber zerumbet

General Information

General Information Comment Organism
evolution the enzyme belongs to the cytochrome P450 monooxygenases Zingiber zerumbet
metabolism CYP71BA1 catalyzes the second step of zerumbone biosynthesis Zingiber zerumbet