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Literature summary for 1.14.14.103 extracted from
- Identification of a low vindoline accumulating cultivar of Catharanthus roseus (L.) G. Don by alkaloid and enzymatic profiling (2006), Phytochemistry, 67, 1758-1764.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Catharanthus roseus | alkaloid and enzymatic profiling of the vindoline biosynthetic pathway, overview | ? | - |
? |  |
| tabersonine + NADPH + H+ + O2 | Catharanthus roseus | step in monoterpenoid indole alkaloid biosynthesis, biosynthesis of anticancer dimeric alkaloids vinblastine and vincristine, overview | 16-hydroxytabersonine + NADP+ + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Catharanthus roseus | - |
50 different flowering cultivars, one low vindoline accumulating cultivar Little Delicata | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | young | Catharanthus roseus | - |
| seedling | - |
Catharanthus roseus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | alkaloid and enzymatic profiling of the vindoline biosynthetic pathway, overview | Catharanthus roseus | ? | - |
? | |
| tabersonine + NADPH + H+ + O2 | - |
Catharanthus roseus | 16-hydroxytabersonine + NADP+ + H2O | - |
? | |
| tabersonine + NADPH + H+ + O2 | step in monoterpenoid indole alkaloid biosynthesis, biosynthesis of anticancer dimeric alkaloids vinblastine and vincristine, overview | Catharanthus roseus | 16-hydroxytabersonine + NADP+ + H2O | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Catharanthus roseus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Catharanthus roseus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome P450 | - |
Catharanthus roseus |
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Release 2023.1 (January 2023)
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