Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Catharanthus roseus | alkaloid and enzymatic profiling of the vindoline biosynthetic pathway, overview | ? | - |
? | |
tabersonine + NADPH + H+ + O2 | Catharanthus roseus | step in monoterpenoid indole alkaloid biosynthesis, biosynthesis of anticancer dimeric alkaloids vinblastine and vincristine, overview | 16-hydroxytabersonine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | - |
50 different flowering cultivars, one low vindoline accumulating cultivar Little Delicata | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | young | Catharanthus roseus | - |
seedling | - |
Catharanthus roseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | alkaloid and enzymatic profiling of the vindoline biosynthetic pathway, overview | Catharanthus roseus | ? | - |
? | |
tabersonine + NADPH + H+ + O2 | - |
Catharanthus roseus | 16-hydroxytabersonine + NADP+ + H2O | - |
? | |
tabersonine + NADPH + H+ + O2 | step in monoterpenoid indole alkaloid biosynthesis, biosynthesis of anticancer dimeric alkaloids vinblastine and vincristine, overview | Catharanthus roseus | 16-hydroxytabersonine + NADP+ + H2O | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Catharanthus roseus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Catharanthus roseus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Catharanthus roseus |