Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 | Papaver somniferum | - |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Papaver somniferum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Papaver somniferum | (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-methylcoclaurine 3'-hydroxylase | - |
Papaver somniferum |
NMCH | - |
Papaver somniferum |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme silencing is associated with a 22% reduction in total alkaloid accumulation, with a notable decrease in the levels of thebaine and codeine compared with controls. In contrast, absolute levels of morphine and papaverine are not affected | Papaver somniferum |