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Literature summary for 1.14.14.1 extracted from

  • Chen, J.S.; Berenbaum, M.R.; Schuler, M.A.
    Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase (2002), Insect Mol. Biol., 11, 175-186.
    View publication on PubMed
Search for more literature for 1.14.14.1

Protein Variants

Protein Variants Comment Organism
F116A no enzymatic activity Papilio polyxenes
F116C no enzymatic activity Papilio polyxenes
F116H no enzymatic activity Papilio polyxenes
F116I no enzymatic activity Papilio polyxenes
F116L no enzymatic activity Papilio polyxenes
F116L/F484L no enzymatic activity Papilio polyxenes
F116L/F484Y no enzymatic activity Papilio polyxenes
F116S no enzymatic activity Papilio polyxenes
F116V no enzymatic activity Papilio polyxenes
F116W some enzymatic activity against bergapten, xanthotoxin Papilio polyxenes
F116Y reduced enzymatic activity Papilio polyxenes
F116Y/F484H no enzymatic activity Papilio polyxenes
F116Y/F484Y no enzymatic activity Papilio polyxenes
F206L no enzymatic activity Papilio polyxenes
F484C no enzymatic activity Papilio polyxenes
F484D no enzymatic activity Papilio polyxenes
F484H no enzymatic activity Papilio polyxenes
F484L no enzymatic activity Papilio polyxenes
F484S no enzymatic activity Papilio polyxenes
F484V no enzymatic activity Papilio polyxenes
F484W no enzymatic activity Papilio polyxenes
F484Y no enzymatic activity Papilio polyxenes
H117A no enzymatic activity Papilio polyxenes
H117F no enzymatic activity Papilio polyxenes
H117L/F484Y no enzymatic activity Papilio polyxenes
H117V no enzymatic activity Papilio polyxenes
H117Y no enzymatic activity Papilio polyxenes
H204L activity similar to wild-type Papilio polyxenes
V368A no enzymatic activity Papilio polyxenes
V368A activity similar to wild-type Papilio polyxenes
V368F no enzymatic activity Papilio polyxenes
V368L no enzymatic activity Papilio polyxenes
V368L activity similar to wild-type Papilio polyxenes

Organism

Organism UniProt Comment Textmining
Papilio polyxenes Q04552 black swallowtail caterpillar
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxy-1-(4-hydroxyphenyl)guanidine + [reduced NADPH-hemoprotein reductase] + O2
-
 Papilio polyxenes ?
-
 ?
bergapten + [reduced NADPH-hemoprotein reductase] + O2
-
 Papilio polyxenes ? + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
isopimpinellin + [reduced NADPH-hemoprotein reductase] + O2
-
 Papilio polyxenes ? + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
psoralen + [reduced NADPH-hemoprotein reductase] + O2
-
 Papilio polyxenes ? + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
xanthotoxin + reduced flavoprotein + O2
-
 Papilio polyxenes ? + oxidized flavoprotein + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP6B1v1
-
 Papilio polyxenes

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Papilio polyxenes