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Literature summary for 1.14.13.9 extracted from

  • Allegri, G.; Bertazzo, A.; Biasiolo, M.; Costa, C.V.; Ragazzi, E.
    Kynurenine pathway enzymes in different species of animals (2003), Adv. Exp. Med. Biol., 527, 455-463.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Cavia porcellus 5739
-
mitochondrion
-
Mus musculus 5739
-
mitochondrion
-
Rattus norvegicus 5739
-
mitochondrion
-
Oryctolagus cuniculus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-kynurenine + NADPH + O2 Cavia porcellus enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 Mus musculus enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 Rattus norvegicus enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 Oryctolagus cuniculus enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Cavia porcellus
-
kidney
-
Mus musculus
-
kidney
-
Rattus norvegicus
-
kidney
-
Oryctolagus cuniculus
-
liver
-
Cavia porcellus
-
liver
-
Mus musculus
-
liver
-
Rattus norvegicus
-
liver
-
Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0005
-
kidney Oryctolagus cuniculus
0.001
-
liver Oryctolagus cuniculus
0.0015
-
activity in liver and in kidney Cavia porcellus
0.0022
-
liver Rattus norvegicus
0.0025
-
liver Mus musculus
0.0025
-
kidney Rattus norvegicus
0.004
-
kidney Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-kynurenine + NADPH + O2
-
Cavia porcellus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2
-
Mus musculus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2
-
Rattus norvegicus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2
-
Oryctolagus cuniculus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview Cavia porcellus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview Mus musculus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview Rattus norvegicus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?
L-kynurenine + NADPH + O2 enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview Oryctolagus cuniculus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
?

Synonyms

Synonyms Comment Organism
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating)
-
Cavia porcellus
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating)
-
Mus musculus
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating)
-
Rattus norvegicus
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating)
-
Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Cavia porcellus
NADPH
-
Mus musculus
NADPH
-
Rattus norvegicus
NADPH
-
Oryctolagus cuniculus