Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Cavia porcellus | 5739 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
mitochondrion | - |
Oryctolagus cuniculus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + NADPH + O2 | Cavia porcellus | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | Mus musculus | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | Rattus norvegicus | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | Oryctolagus cuniculus | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Mus musculus | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Cavia porcellus | - |
kidney | - |
Mus musculus | - |
kidney | - |
Rattus norvegicus | - |
kidney | - |
Oryctolagus cuniculus | - |
liver | - |
Cavia porcellus | - |
liver | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0005 | - |
kidney | Oryctolagus cuniculus |
0.001 | - |
liver | Oryctolagus cuniculus |
0.0015 | - |
activity in liver and in kidney | Cavia porcellus |
0.0022 | - |
liver | Rattus norvegicus |
0.0025 | - |
liver | Mus musculus |
0.0025 | - |
kidney | Rattus norvegicus |
0.004 | - |
kidney | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + NADPH + O2 | - |
Cavia porcellus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | - |
Mus musculus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | - |
Rattus norvegicus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | - |
Oryctolagus cuniculus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | Cavia porcellus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | Mus musculus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | Rattus norvegicus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? | |
L-kynurenine + NADPH + O2 | enzyme is involved in L-tryptophan catabolism, pathway regulation in comparison to other species, overview | Oryctolagus cuniculus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating) | - |
Cavia porcellus |
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating) | - |
Mus musculus |
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating) | - |
Rattus norvegicus |
L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating) | - |
Oryctolagus cuniculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Cavia porcellus | |
NADPH | - |
Mus musculus | |
NADPH | - |
Rattus norvegicus | |
NADPH | - |
Oryctolagus cuniculus |