Activating Compound | Comment | Organism | Structure |
---|---|---|---|
n-octylamine | 3 mM, enhances activity by 51% | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
expression in yeast cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-naphthylthiourea | 0.5 mM, 59.2% inhibition | Rattus norvegicus | |
Methimazole | 0.5 mM, 27.4% inhibition | Rattus norvegicus | |
thiobenzamide | 0.5 mM, 68% inhibition | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0018 | - |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 | Rattus norvegicus | one of the predominant enzmyes responsible for the oxygenation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 | - |
Rattus norvegicus | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O | - |
? | |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 | one of the predominant enzmyes responsible for the oxygenation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Rattus norvegicus | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | flavoprotein | Rattus norvegicus |