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Literature summary for 1.14.13.8 extracted from
- Inhibition of purified and membrane-bound flavin-containing monooxygenase 1 by (N,N-dimethylamino)stilbene carboxylates (1996), Chem. Res. Toxicol., 9, 599-604.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (E)-2-[2-(4-(dimethylamino)phenyl)vinyl]benzoic acid | i.e. DS2CO, 2 mM, mechanism | Sus scrofa |  |
| (E)-3-[2-(4-(dimethylamino)phenyl)vinyl]benzoic acid | 2 mM, 80-90% inhibition, mechansim; i.e. DS3CO | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| imipramine + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| methimazole + NADPH + O2 | - |
Sus scrofa | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
| tamoxifen + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| trifluoperazine + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
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