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Literature summary for 1.14.13.64 extracted from

  • Holesova, Z.; Jakubkova, M.; Zavadiakova, I.; Zeman, I.; Tomaska, L.; Nosek, J.
    Gentisate and 3-oxoadipate pathways in the yeast Candida parapsilosis: identification and functional analysis of the genes coding for 3-hydroxybenzoate 6-hydroxylase and 4-hydroxybenzoate 1-hydroxylase (2011), Microbiology, 157, 2152-2163.
    View publication on PubMed
Search for more literature for 1.14.13.64

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Candida parapsilosis 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 x * 50000, SDS-PAGE Candida parapsilosis
52600
-
 x * 52600, calculated from amino acid sequence Candida parapsilosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,4-dihydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis
-
 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
2,4-dihydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis CDU1
-
 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
3,4-dihydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis
-
 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
3,4-dihydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis CDU1
-
 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
4-hydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis
-
 hydroquinone + NAD(P)+ + H2O + CO2
-
 ?
4-hydroxybenzoate + NAD(P)H + H+ + O2 Candida parapsilosis CDU1
-
 hydroquinone + NAD(P)+ + H2O + CO2
-
 ?
protocatechuate + NAD(P)H + H+ + O2 Candida parapsilosis
-
 ?
-
 ?
protocatechuate + NAD(P)H + H+ + O2 Candida parapsilosis CDU1
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Candida parapsilosis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-dihydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
2,4-dihydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis CDU1 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
3,4-dihydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
3,4-dihydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis CDU1 benzene-1,2,4-triol + NAD(P)+ + H2O + CO2
-
 ?
4-hydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis hydroquinone + NAD(P)+ + H2O + CO2
-
 ?
4-hydroxybenzoate + NAD(P)H + H+ + O2
-
 Candida parapsilosis CDU1 hydroquinone + NAD(P)+ + H2O + CO2
-
 ?
protocatechuate + NAD(P)H + H+ + O2
-
 Candida parapsilosis ?
-
 ?
protocatechuate + NAD(P)H + H+ + O2
-
 Candida parapsilosis CDU1 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Candida parapsilosis
? x * 52600, calculated from amino acid sequence Candida parapsilosis

Synonyms

Synonyms Comment Organism
MNX1
-
 Candida parapsilosis
Mnx1p
-
 Candida parapsilosis

Cofactor

Cofactor Comment Organism Structure
flavin
-
 Candida parapsilosis
NADH
-
 Candida parapsilosis
NADPH
-
 Candida parapsilosis

General Information

General Information Comment Organism
physiological function overexpression of the enzyme increases the tolerance of Candida parapsilosis cells to the antifungal drug terbinafine Candida parapsilosis