Literature summary for 1.14.13.39 extracted from

Nishida, C.R.; Ortiz de Montellano, P.R.
Reductive heme-dependent activation of the n-oxide prodrug AQ4N by nitric oxide synthase (2008), J. Med. Chem., 51, 5118-5120.

Search for more literature for 1.14.13.39

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P35228	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,4-bis-[[2-(dimethylamino-N-oxide)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione + NADPH	-	Homo sapiens	1-[[2-(dimethylamino-N-oxide)ethyl]amino]-4-[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione + ?	-	ir
1-[[2-(dimethylamino-N-oxide)ethyl]amino]-4-[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione + NADPH	-	Homo sapiens	1,4-bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione + ?	-	ir

Synonyms

Synonyms	Comment	Organism
inducible nitric oxide synthase	-	Homo sapiens
iNOS	-	Homo sapiens
NOS-2	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Homo sapiens

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Release 2023.1 (January 2023)