BRENDA - Enzyme Database show
show all sequences of 1.14.13.25

A novel methanotroph in the genus Methylomonas that contains a distinct clade of soluble methane monooxygenase

Nguyen, N.L.; Yu, W.J.; Yang, H.Y.; Kim, J.G.; Jung, M.Y.; Park, S.J.; Roh, S.W.; Rhee, S.K.; J. Microbiol. 55, 775-782 (2017)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Methylomonas sp.
5737
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Methylomonas sp.
A0A250DUW2
mmoX encodes the alpha-unit of soluble methane monooxygenase
-
Methylomonas sp. EMGL16-1
A0A250DUW2
mmoX encodes the alpha-unit of soluble methane monooxygenase
-
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Methylomonas sp.
5737
-
Other publictions for EC 1.14.13.25
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
744688
Wang
Alkane oxidation methane mono ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Chem. Rev.
117
8574-8621
2017
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744939
Lock
Mutagenesis and expression of ...
Methylosinus trichosporium
FEMS Microbiol. Lett.
364
fnx137
2017
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745177
Castillo
High-energy-resolution fluore ...
Methylosinus trichosporium
J. Am. Chem. Soc.
139
18024-18033
2017
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745389
Ross
A tale of two methane monooxy ...
Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylococcus capsulatus Bath.
J. Biol. Inorg. Chem.
22
307-319
2017
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1
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3
1
3
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47
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1
3
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5
1
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2
2
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745453
Zhang
Coupled effects of methane mo ...
Methylosinus trichosporium
J. Environ. Sci.
52
49-57
2017
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1
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745536
Nguyen
A novel methanotroph in the g ...
Methylomonas sp., Methylomonas sp. EMGL16-1
J. Microbiol.
55
775-782
2017
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1
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746420
Zhang
-
Low-temperature biological ac ...
Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylosinus trichosporium
Rev. Environ. Sci. Biotechnol.
16
611-623
2017
-
1
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3
2
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3
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42
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1
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3
1
2
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1
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6
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1
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6
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2
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3
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3
1
2
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1
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2
2
-
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744797
Vekeman
New Methyloceanibacter divers ...
Methyloceanibacter methanicus, Methyloceanibacter methanicus R-67174
Environ. Microbiol.
18
4523-4536
2016
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1
1
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745535
Lee
Hydroxylation of methane thro ...
Methylococcus capsulatus, Methylococcus capsulatus Bath., Methylosinus trichosporium
J. Microbiol.
54
277-282
2016
-
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2
1
1
3
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8
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1
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6
1
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2
2
2
2
-
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745730
Larsen
Transcriptomic profiling of M ...
Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylococcus capsulatus Bath.
MicrobiologyOpen
5
254-267
2016
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1
1
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3
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48
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1
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2
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744098
Kalidass
Competition between metals fo ...
Methylosinus trichosporium OB3b
Appl. Environ. Microbiol.
81
1024-1031
2015
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1
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3
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1
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1
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744100
Farhan Ul-Haque
Methanobactin from Methylocys ...
Methylosinus trichosporium
Appl. Environ. Microbiol.
81
2466-2473
2015
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1
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1
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2
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1
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1
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1
1
1
1
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744507
Sigdel
Molecular dynamics simulation ...
Methylosinus trichosporium OB3b
Bioorg. Med. Chem. Lett.
25
1611-1615
2015
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745039
Dedysh
Draft genome sequence of Meth ...
Methyloferula stellata AR4
Genome Announc.
3
e1555-14
2015
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1
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3
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1
1
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745157
Wang
Diiron oxidation state contro ...
Methylococcus capsulatus, Methylococcus capsulatus Bath.
J. Am. Chem. Soc.
136
2244-2247
2014
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1
1
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6
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2
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745159
Wang
Electron transfer control in ...
Methylococcus capsulatus, Methylococcus capsulatus Bath.
J. Am. Chem. Soc.
136
9754-9762
2014
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1
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7
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728376
Lee
Control of substrate access to ...
Methylococcus capsulatus
Nature
494
380-384
2013
1
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1
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1
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712199
Vorobev
Methyloferula stellata gen. no ...
Methyloferula stellata, Methyloferula stellata AR4T, Methyloferula stellata gen. nov., sp. nov., Methyloferula stellata LAY, Methyloferula stellata SOP9
Int. J. Syst. Evol. Microbiol.
61
2456-2463
2011
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1
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1
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19
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726546
Tinberg
Dioxygen activation in soluble ...
Methylococcus capsulatus
Acc. Chem. Res.
44
280-288
2011
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711260
Tinberg
Oxidation reactions performed ...
Methylococcus capsulatus
Biochemistry
49
7902-7912
2010
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1
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712040
Iguchi
Soluble and particulate methan ...
Methylovulum miyakonense, Methylovulum miyakonense HT12
FEMS Microbiol. Lett.
312
71-76
2010
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1
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1
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6
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701759
Zhang
The methane monooxygenase intr ...
Methylococcus capsulatus, Methylococcus capsulatus HD6T, Methylomonas sp., Methylomonas sp. GYJ3, Methylosinus trichosporium
Appl. Biochem. Biotechnol.
157
431-441
2009
-
3
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6
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4
6
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10
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23
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6
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6
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23
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3
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3
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701836
Yu
Use of allylthiourea to produc ...
Methylosinus trichosporium OB3b
Appl. Microbiol. Biotechnol.
82
333-339
2009
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1
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703211
Siewert
Low-molecular-weight analogues ...
Bacteria
Chemistry
15
10316-10328
2009
-
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1
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1
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703761
Scanlan
Involvement of MmoR and MmoG i ...
Methylosinus trichosporium OB3b
FEMS Microbiol. Lett.
301
181-187
2009
-
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1
1
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1
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1
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704758
Yu
Production of soluble methane ...
Methylosinus trichosporium OB3b
J. Biotechnol.
139
78-83
2009
1
1
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685262
Hakemian
The metal centers of particula ...
Methylosinus trichosporium
Biochemistry
47
6793-6801
2008
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685272
Mitic
CD and MCD studies of the effe ...
Methylosinus trichosporium
Biochemistry
47
8386-8397
2008
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704019
Han
Structural model studies for t ...
synthetic construct
Inorg. Chim. Acta
361
973-986
2008
1
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704171
Schwartz
Geometric and electronic struc ...
synthetic construct
J. Am. Chem. Soc.
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2008
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706752
Anthony
A tribute to Howard Dalton and ...
Methylococcus capsulatus
Sci. Prog.
91
401-415
2008
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11
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672690
Shaofeng
Purification and biochemical c ...
Methylosinus trichosporium, Methylosinus trichosporium IMV 3011
Biosci. Biotechnol. Biochem.
71
122-129
2007
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4
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4
2
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1
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4
2
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1
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1
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684566
Borodina
Mutagenesis of the 'leucine ga ...
Methylosinus trichosporium
Appl. Environ. Microbiol.
73
6460-6467
2007
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4
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6
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671477
Lee
Mixed pollutant degradation by ...
Methylosinus trichosporium
Appl. Environ. Microbiol.
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7503-7509
2006
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672049
Ukaegbu
Biochemical characterization o ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochemistry
45
10191-10198
2006
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1
1
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43
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4
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672102
Zhang
Role of the C-terminal region ...
Methylosinus trichosporium
Biochemistry
45
1459-1469
2006
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1
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1
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1
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1
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672130
Zhang
Methane monooxygenase hydroxyl ...
Methylosinus trichosporium
Biochemistry
45
2913-2926
2006
-
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-
13
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1
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1
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1
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2
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13
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1
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1
1
1
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1
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675083
Herrmann
Spin states in polynuclear clu ...
methylotrophic bacterium
J. Comput. Chem.
27
1223-1239
2006
-
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1
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675455
Zhang
-
Basis for specificity in metha ...
Methylophilaceae
J. Mol. Catal. A
251
54-65
2006
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3
1
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-
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-
676844
Stoecker
Cohns Crenothrix is a filament ...
Crenothrix polyspora
Proc. Natl. Acad. Sci. USA
103
2363-2367
2006
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1
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5
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1
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-
-
-
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-
-
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-
671721
Liu
Substrate radical intermediate ...
Methylosinus trichosporium
Biochem. Biophys. Res. Commun.
338
254-261
2005
-
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1
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1
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1
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5
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1
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1
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5
-
1
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1
-
-
-
-
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-
-
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-
671722
Beauvais
Reactions of the diiron(IV) in ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochem. Biophys. Res. Commun.
338
262-266
2005
-
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1
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1
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2
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41
-
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1
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1
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10
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1
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1
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1
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1
1
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1
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1
-
10
-
1
-
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-
1
-
-
-
-
-
-
-
-
-
673999
Rudd
X-ray absorption spectroscopic ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Inorg. Chem.
44
4546-4554
2005
-
-
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1
-
-
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1
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2
-
41
-
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4
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1
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1
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1
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1
1
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1
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2
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-
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4
-
1
-
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1
-
-
-
-
-
-
-
-
-
-
674145
Gherman
Substrate hydroxylation in met ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Am. Chem. Soc.
127
1025-1037
2005
-
-
-
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1
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2
-
41
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1
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1
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4
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1
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1
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1
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674158
Blazyk
Intermolecular electron-transf ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Am. Chem. Soc.
127
17364-17376
2005
-
-
-
-
-
-
2
1
1
1
-
2
-
41
-
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1
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4
1
1
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1
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3
-
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3
-
-
-
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2
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1
1
1
-
2
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-
-
-
-
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
674170
Beauvais
Reactions of the peroxo interm ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Am. Chem. Soc.
127
7370-7378
2005
-
-
-
-
-
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1
1
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2
-
42
-
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1
1
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1
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4
-
1
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1
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1
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1
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1
1
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2
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1
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1
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
658051
Sazinsky
Preparation and X-ray structur ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochemistry
43
16263-16276
2004
-
-
-
1
-
-
-
-
1
-
-
-
-
42
-
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2
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1
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1
1
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1
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-
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-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657998
Brazeau
Key amino acid residues in the ...
Methylosinus trichosporium
Biochemistry
42
5618-5631
2003
-
-
-
-
1
-
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1
-
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1
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4
-
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1
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1
-
1
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1
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-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658632
Astier
Cofactor-independent oxygenati ...
Methylococcus capsulatus
Eur. J. Biochem.
270
539-544
2003
1
1
-
-
-
-
-
-
-
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-
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1
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-
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1
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1
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1
1
-
1
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
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438943
Merkx
Why orfY? Characterization of ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Biol. Chem.
277
5858-5865
2002
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1
1
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4
3
1
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1
1
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3
-
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1
3
-
-
1
-
1
-
-
1
-
2
-
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1
-
-
-
-
4
3
1
-
-
1
1
-
-
-
-
-
-
-
-
-
438942
Murrell
Molecular biology and regulati ...
Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylocystis sp., Methylomicrobium album, Methylomicrobium album BG8
Arch. Microbiol.
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325-332
2000
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3
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15
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-
-
-
-
-
-
15
-
-
-
-
-
-
-
-
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6
-
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438946
Lontoh
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Dichloromethane and trichloroe ...
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Grosse
Purification and characterizat ...
Methylocystis sp., Methylocystis sp. WI 14
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3
28
1
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1
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438949
Brandstetter
Mutational and structural anal ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
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1
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4
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2
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Purification and characterizat ...
Methylocystis sp.
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438945
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Inactivation of the regulatory ...
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1
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1
1
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2
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1
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1
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1
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1
-
1
-
-
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-
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-
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-
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-
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-
-
-
-
438948
Jahng
-
Metal ions and chloramphenicol ...
Methylosinus trichosporium
Appl. Microbiol. Biotechnol.
45
744-749
1996
-
-
1
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8
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1
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1
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2
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8
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1
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1
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1
-
-
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-
-
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-
-
-
-
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-
-
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-
438925
Pilkington
-
Purification and characterizat ...
Methylosinus sporium, Methylosinus sporium 5
FEMS Microbiol. Lett.
78
103-108
1991
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-
-
-
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1
1
5
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2
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1
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2
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2
2
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2
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2
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1
1
5
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1
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2
-
2
2
-
-
-
-
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-
-
-
-
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-
-
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-
438933
Fox
Complex formation between the ...
Methylosinus trichosporium
J. Biol. Chem.
266
540-550
1991
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-
-
-
-
-
-
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1
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1
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1
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1
1
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2
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2
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1
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-
1
1
-
-
-
-
-
-
-
-
-
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-
-
-
438934
Rataj
Oxidation of deuterated compou ...
Methylosinus trichosporium
J. Biol. Chem.
266
18684-18690
1991
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-
-
-
-
-
-
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1
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1
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1
1
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14
1
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1
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1
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1
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1
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-
14
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438923
Pilkington
-
Soluble methane monooxygenase ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Methods Enzymol.
188
181-190
1990
-
-
-
-
-
3
1
4
1
1
4
2
-
41
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1
1
-
-
4
-
21
2
1
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
3
-
1
-
4
1
1
4
2
-
-
-
1
-
-
4
-
21
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
438924
Fox
Methane monooxygenase from Met ...
Methylosinus trichosporium
Methods Enzymol.
188
191-202
1990
-
-
-
-
-
-
-
3
-
1
7
1
-
1
-
-
1
-
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-
1
1
4
2
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-
-
3
1
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-
2
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-
-
2
-
-
-
-
-
-
3
-
1
7
1
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1
-
-
1
1
4
2
-
-
-
3
1
-
-
-
-
-
-
-
-
-
438932
Dalton
-
Towards a unified mechanism of ...
Methylobacterium sp., Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylosinus trichosporium
FEMS Microbiol. Lett.
87
201-208
1990
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-
-
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3
3
3
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43
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3
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4
3
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-
-
-
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-
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7
-
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7
-
-
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3
3
3
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-
-
4
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438937
Green
Substrate specificity of solub ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Biol. Chem.
264
17698-17703
1989
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-
-
-
-
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1
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42
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1
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20
-
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1
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1
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1
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-
-
20
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
438941
Fox
Methane monooxygenase from Met ...
Methylosinus trichosporium
J. Biol. Chem.
264
10023-10033
1989
-
-
-
-
-
-
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-
1
3
-
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1
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1
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-
1
-
1
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-
2
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-
2
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1
3
-
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1
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1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438935
Fox
Purification of a high specifi ...
Methylosinus trichosporium
Biochem. Biophys. Res. Commun.
154
165-170
1988
-
-
-
-
-
-
-
-
-
1
2
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-
4
-
-
1
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-
1
-
1
1
1
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-
1
-
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-
1
-
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-
1
-
-
-
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-
-
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-
1
2
-
-
-
-
1
-
-
1
-
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
438926
Patel
Purification and properties of ...
Methylobacterium sp.
J. Bacteriol.
169
2313-2317
1987
-
-
-
-
-
-
-
-
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2
5
-
-
1
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-
1
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-
1
-
1
2
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-
1
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-
1
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2
5
-
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1
-
-
1
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438928
Lund
Further characterisation of th ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Eur. J. Biochem.
147
291-296
1985
-
-
-
-
-
-
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2
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43
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2
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2
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2
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2
-
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438929
Green
Copper ions as inhibitors of p ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Eur. J. Biochem.
153
137-144
1985
-
-
-
-
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7
-
1
1
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-
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42
-
-
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-
1
-
2
-
-
-
-
-
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-
-
1
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-
1
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-
-
7
-
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1
1
-
-
-
-
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-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438930
Green
Protein B of soluble methane m ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Biol. Chem.
260
15795-15801
1985
-
-
-
-
-
1
-
1
-
1
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-
-
42
-
-
1
-
-
-
1
-
2
-
1
-
1
-
-
-
1
1
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
2
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
438931
Woodland
Purification and characterizat ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
J. Biol. Chem.
259
53-59
1984
-
-
-
-
-
-
-
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2
5
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41
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1
-
-
-
1
1
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
5
-
-
-
-
1
-
-
1
1
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438922
Stirling
Properties of the methane mono ...
Methylococcus capsulatus, Methylococcus capsulatus Bath, Methylosinus trichosporium
Eur. J. Biochem.
96
205-212
1979
-
-
-
-
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2
4
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2
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2
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45
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-
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-
-
-
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-
6
4
-
-
-
-
-
-
-
2
-
-
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-
-
2
-
-
2
-
4
-
-
2
-
2
-
-
-
-
-
-
-
-
-
6
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438938
Colby
Characterization of the second ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochem. J.
177
903-908
1979
-
-
-
-
-
1
2
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-
1
1
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43
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-
1
-
-
-
1
-
4
1
1
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
1
-
2
-
-
-
1
1
-
-
-
-
1
-
-
1
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
438939
Colby
Resolution of the methane mono ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochem. J.
171
461-468
1978
-
-
-
-
-
-
-
-
1
2
2
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-
42
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-
1
-
-
-
1
2
4
1
-
-
1
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
2
2
-
-
-
-
1
-
-
1
2
4
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
438920
Colby
The soluble methane mono-oxyge ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochem. J.
165
395-402
1977
-
-
-
-
-
-
-
-
1
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-
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45
-
-
-
-
-
-
1
-
28
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
28
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438921
Tonge
Purification and properties of ...
Methylosinus trichosporium
Biochem. J.
161
333-344
1977
-
-
-
-
-
1
13
1
-
2
4
-
-
5
-
-
1
-
-
-
2
-
6
2
-
-
-
-
1
1
-
3
-
-
-
-
-
-
3
-
-
1
-
13
-
1
-
2
4
-
-
-
-
1
-
-
2
-
6
2
-
-
-
-
1
1
-
-
-
-
-
-
-
-
438936
Colby
Some properties of a soluble m ...
Methylococcus capsulatus, Methylococcus capsulatus Bath
Biochem. J.
157
495-497
1976
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-
-
-
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-
3
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1
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42
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-
-
-
-
-
4
-
1
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-