Cloned (Comment) | Organism |
---|---|
expression in Streptomyces lividans | Streptomyces cremeus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-amino-4-hydroxybenzoate + NADPH + H+ + O2 | Streptomyces cremeus | - |
3-amino-2,4-dihydroxybenzoate + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces cremeus | A0A0K2JKU1 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-amino-4-hydroxybenzoate + NADPH + H+ + O2 | - |
Streptomyces cremeus | 3-amino-2,4-dihydroxybenzoate + NADP+ + H2O | - |
? | |
additional information | no substrate: 3-amino-4-methoxybenzoic acid | Streptomyces cremeus | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
creL | - |
Streptomyces cremeus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Streptomyces cremeus |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme is part of the gene cluster that produces the o-diazoquinone natural product cremeomycin, involved in 3-amino-4-hydroxybenzoic acid synthesis and tailoring. During biosynthesis, hydroxylation precedes O-methylation in the transformation of 3-amino-4-hydroxybenzoate to 3-amino-2-hydroxy-4-methoxybenzoic acid | Streptomyces cremeus |