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Literature summary for 1.14.13.242 extracted from

  • Chaiyen, P.; Sucharitakul, J.; Svasti, J.; Entsch, B.; Massey, V.; Ballou, D.P.
    Use of 8-substituted-FAD analogues to investigate the hydroxylation mechanism of the flavoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (2004), Biochemistry, 43, 3933-3943.
    View publication on PubMed
Search for more literature for 1.14.13.242

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-

Reaction

Reaction Comment Organism Reaction ID
3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + H+ + O2 = 2-(acetamidomethylidene)succinate + NAD(P)+ oxygenation reaction occurs via an electrophilic aromatic substitution mechanism Pseudomonas sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + H+ + O2
-
 Pseudomonas sp. 2-(acetamidomethylene)succinate + NAD(P)+
-
 ?
5-hydroxynicotinate + NAD(P)H + H+ + O2
-
 Pseudomonas sp. ? + NAD(P)+
-
 ?

Cofactor

Cofactor Comment Organism Structure
FAD investigation of reaction using various FAD analogs Pseudomonas sp.
NAD(P)H
-
 Pseudomonas sp.