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Literature summary for 1.14.13.225 extracted from

  • Hung, R.J.; Yazdani, U.; Yoon, J.; Wu, H.; Yang, T.; Gupta, N.; Huang, Z.; van Berkel, W.J.; Terman, J.R.
    Mical links semaphorins to F-actin disassembly (2010), Nature, 463, 823-827.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q86BA1
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General Information

General Information Comment Organism
physiological function Mical is both necessary and sufficient for semaphorin-plexin mediated F-actin reorganization in vivo. Mical directly binds F-actin and disassembles both individual and bundled actin filaments. Mical utilizes its redox activity to alter F-actin dynamics in vivo and in vitro Drosophila melanogaster