Application | Comment | Organism |
---|---|---|
synthesis | production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes | Acinetobacter sp. |
Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli and Saccharomyces cerevisiae | Acinetobacter sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-dithiane sulfoxide + NADPH + O2 | Acinetobacter sp. | recombinant enzyme in E. coli or Saccharomyces cerevisiae | ? | - |
? | |
dithiane + NADPH + H+ + O2 | Acinetobacter sp. | recombinant enzyme in E. coli or Saccharomyces cerevisiae | (R)-dithiane sulfoxide + NADP+ + H2O | - |
? | |
methyl phenyl sulfide + NADPH + H+ + O2 | Acinetobacter sp. | recombinant enzyme in E. coli or Saccharomyces cerevisiae | (R)-methyl phenyl sulfoxide + NADP+ + H2O | - |
? | |
additional information | Acinetobacter sp. | production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes | ? | - |
? | |
n-butyl methyl sulfide + NADPH + O2 | Acinetobacter sp. | recombinant enzyme in E. coli or Saccharomyces cerevisiae | ? | - |
? | |
tert-butyl methyl sulfide + NADPH + O2 | Acinetobacter sp. | recombinant enzyme in E. coli or Saccharomyces cerevisiae | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter sp. | - |
NCIB 9871 | - |
Purification (Comment) | Organism |
---|---|
recombinant from Escherichia coli and Saccharomyces cerevisiae | Acinetobacter sp. |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O | enantioselectivity | Acinetobacter sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-dithiane sulfoxide + NADPH + O2 | recombinant enzyme in E. coli or Saccharomyces cerevisiae | Acinetobacter sp. | ? | - |
? | |
dithiane + NADPH + H+ + O2 | recombinant enzyme in E. coli or Saccharomyces cerevisiae | Acinetobacter sp. | (R)-dithiane sulfoxide + NADP+ + H2O | - |
? | |
methyl phenyl sulfide + NADPH + H+ + O2 | recombinant enzyme in E. coli or Saccharomyces cerevisiae | Acinetobacter sp. | (R)-methyl phenyl sulfoxide + NADP+ + H2O | - |
? | |
additional information | production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes | Acinetobacter sp. | ? | - |
? | |
n-butyl methyl sulfide + NADPH + O2 | recombinant enzyme in E. coli or Saccharomyces cerevisiae | Acinetobacter sp. | ? | - |
? | |
tert-butyl methyl sulfide + NADPH + O2 | recombinant enzyme in E. coli or Saccharomyces cerevisiae | Acinetobacter sp. | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Acinetobacter sp. |