Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.13.181 extracted from

  • Dickens, M.L.; Strohl, W.R.
    Isolation and characterization of a gene from Streptomyces sp. strain C5 that confers the ability to convert daunomycin to doxorubicin on Streptomyces lividans TK24 (1996), J. Bacteriol., 178, 3389-3395.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.13.181

Cloned(Commentary)

Cloned (Comment) Organism
expression in Streptomyces lividans TK24 Streptomyces sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46096
-
 x * 46096, calculated from sequence Streptomyces sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Streptomyces sp. the enzyme convert daunomycin to doxorubicin ?
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces sp. Q59971
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme convert daunomycin to doxorubicin Streptomyces sp. ?
-
 ?
additional information daunomycinone (daunomycin aglycone), carminomycin, 13-dihydrocarminomycin, idarubicin, and aklavin are not apparent substrates for DoxA Streptomyces sp. ?
-
 ?

Subunits

Subunits Comment Organism
? x * 46096, calculated from sequence Streptomyces sp.

Synonyms

Synonyms Comment Organism
DoxA
-
 Streptomyces sp.