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Literature summary for 1.14.13.111 extracted from

  • de Marco, P.; Moradas-Ferreira, P.; Higgins, T.P.; McDonald, I.; Kenna, E.M.; Murrell, J.C.
    Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora (1999), J. Bacteriol., 181, 2244-2251.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.13.111

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli. The four polypeptides comprising MSAMO are the products of the coordinated expression of an operon (msmABCD) Methylosulfonomonas methylovora

Metals/Ions

Metals/Ions Comment Organism Structure
Iron the enzyme contains a two-component hydroxylase of the mononuclear-iron-center type. The large subunit of the hydroxylase (MsmA) contains a typical Rieske-type [2Fe–2S] center with an unusual iron-binding motif. The reductase component (MsmD) possesses a typical chloroplast-like [2Fe–2S] center Methylosulfonomonas methylovora

Organism

Organism UniProt Comment Textmining
Methylosulfonomonas methylovora
-
-
-
Methylosulfonomonas methylovora M2
-
-
-

Subunits

Subunits Comment Organism
? multicomponent enzyme contains a two-component hydroxylase of the mononuclear-iron-center type. The large subunit of the hydroxylase, MsmA (48473 Da calculated from sequence), contains a typical Rieske-type [2Fe–2S] center with an unusual iron-binding motif. The small subunit of the hydroxylase, MsmB (20478 Da calculated from sequence). MsmC (13748 Da calculated from sequence) is the ferredoxin component, and MsmD (388520 Da calculated from sequence) is the reductase component Methylosulfonomonas methylovora

Synonyms

Synonyms Comment Organism
MSA monooxygenase
-
 Methylosulfonomonas methylovora
MSAMO
-
 Methylosulfonomonas methylovora

pI Value

Organism Comment pI Value Maximum pI Value
Methylosulfonomonas methylovora MsmC, ferredoxin component, calculated from sequence
-
 3.9
Methylosulfonomonas methylovora MsmB, small subunit of hydroxylase component, calculated from sequence
-
 5.6
Methylosulfonomonas methylovora MsmD, ferredoxin component, calculated from sequence
-
 6.5
Methylosulfonomonas methylovora MsmA, small subunit of hydroxylase component, calculated from sequence
-
 6.7