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Literature summary for 1.14.12.17 extracted from
- Consumption of nitric oxide by endothelial cells: evidence for the involvement of a NAD(P)H-, flavin- and heme-dependent dioxygenase reaction (2004), FEBS Lett., 577, 199-204.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diphenylene iodonium | 0.1 mM | Sus scrofa |  |
| NaCN | 1 mM | Sus scrofa | |
| phenylhydrazine | - |
Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | associated | Sus scrofa | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta | endothelial cells | Sus scrofa | - |
| endothelial cell | from aorta | Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NO + O2 + NADH | - |
Sus scrofa | NO3- + NAD+ + H+ | - |
? | |
| NO + O2 + NADPH | - |
Sus scrofa | NO3- + NADP+ + H+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | slightly more potent than NADPH | Sus scrofa | |
| NADPH | - |
Sus scrofa | |
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Release 2023.1 (January 2023)
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