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Literature summary for 1.14.12.12 extracted from

  • Lee, K.; Resnick, S.M.; Gibson, D.T.
    Stereospecific oxidation of (R)- and (S)-1-indanol by naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4 (1997), Appl. Environ. Microbiol., 63, 2067-2070.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
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 strain NCIB 9816/11, naphthalene dihydrogenase mutant derived from strain NCIB 9816-4 oxidizing naphthalene to cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-1-indanol + NADH + H+ + O2 activity in E. coli cells expressing recombinant naphthalene dioxygenase Pseudomonas sp. cis-1,3-indandiol + (R)-3-hydroxy-1-indanone + cis-1,2,3-indantriol + NAD+ 71% cis-1,3-indandiol, 18.2% (R)-3-hydroxy-1-indanone and 10.8% cis-1,2,3-indantriol ?
(S)-1-indanol + NADH + H+ + O2 activity in E. coli cells expressing recombinant naphthalene dioxygenase Pseudomonas sp. trans-(1S,3S)-indan-1,3-diol + (R)-3-hydroxy-1-indanone + NAD+ 95.5% trans-(1S,3S)-indan-1,3-diol ?
(S)-1-indenol + NADH + O2 recombinant enzyme system Pseudomonas sp. syn-2,3-dihydroxy-1-indanol + anti-2,3-dihydroxy-1-indanol
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 ?