Cloned (Comment) | Organism |
---|---|
gene F3H-B1 and a fourth gene F3H-B2, a nonhomologous duplication of F3H-B1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree | Triticum aestivum |
gene F3H-D1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree | Triticum aestivum |
gene F3HA1, DNA and amiino acid sequence determination and analysis, sequence comparisons and phylogenetic tree, a recognition site of bZIP-type transcription factor (bZIP911) occurs in the promoter of F3H-A1 | Triticum aestivum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | required, two histidines and one aspartic acid of the pfam03171 motif are sites for putative iron binding | Triticum aestivum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
a flavanone + 2-oxoglutarate + O2 | Triticum aestivum | - |
a dihydroflavonol + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Triticum aestivum | C0SPH1 | gene F3HA1; diverse wheat lines, F3H gene F3HA1 | - |
Triticum aestivum | C0SPH2 | gene F3H-B1; diverse wheat lines, F3H gene F3H-B1, and a fourth gene F3H-B2, a nonhomologous duplication of F3H-B1 | - |
Triticum aestivum | C0SPH3 | gene F3H-D1; diverse wheat lines, F3H gene F3H-D1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
coleoptile | - |
Triticum aestivum | - |
additional information | the F3H gene is highly activated in the red grains and coleoptiles, no expression in white grains | Triticum aestivum | - |
additional information | the F3H gene is highly activated in the red grains and coleoptiles, only slight expression in white grains | Triticum aestivum | - |
seed | - |
Triticum aestivum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
a flavanone + 2-oxoglutarate + O2 | - |
Triticum aestivum | a dihydroflavonol + succinate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
F3H | - |
Triticum aestivum |
flavanone 3-hydroxylase | - |
Triticum aestivum |
General Information | Comment | Organism |
---|---|---|
evolution | the F3H isozymes have a unique motif of pfam03171 that is maintained in the superfamily of 2-oxoglutarate and Fe(II)-dependent oxygenases | Triticum aestivum |
metabolism | flavanone 3-hydroxylase is a key enzyme at a diverging point of the flavonoid pathway leading to production of different pigments: phlobaphene, proanthocyanidin, and anthocyanin, flavonoid biosynthetic pathway, overview | Triticum aestivum |
physiological function | the enzyme is involved in the red pigmentation of grain tissues, overview | Triticum aestivum |