Any feedback?
Literature summary for 1.14.11.68 extracted from
- The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment (2008), PLoS ONE, 3, e3404 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Mus musculus | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q5NCY0 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryonic stem cell | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| JMJD3 | - |
Mus musculus |
| KDM6B | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | Jmjd3 expression is upregulated at the outset of neural commitment | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | during the monolayer differentiation of mouse embryonic stem cells into neural stem cells, Jmjd3 controls the expression of key regulators and markers of neurogenesis and is required for commitment to the neural lineage. Jmjd3 targets show distinct patterns of H3K27 methylation and expression | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
