Literature summary for 1.14.11.68 extracted from

Kamikawa, Y.F.; Donohoe, M.E.
The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated (2014), Epigenetics, 9, 834-841 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	embryonic fibroblasts display a dynamic nucleocytoplasmic shuttling of endogenous Jmjd3. Jmjd3 is localized both into the cytoplasm and the nucleus, and its nuclear export is dependent on exportin-1	Mus musculus	5737	-
nucleus	embryonic fibroblasts display a dynamic nucleocytoplasmic shuttling of endogenous Jmjd3. Jmjd3 is localized both into the cytoplasm and the nucleus, and its nuclear export is dependent on exportin-1	Mus musculus	5634	-
nucleus	nuclear localization of Jmjd3 is required for effective demethylation of H3K27me3. The N-terminal region of the protein is responsible for its nuclear placement	Homo sapiens	5634	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15054	-	-
Mus musculus	Q5NCY0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	-	Mus musculus	-

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Release 2023.1 (January 2023)