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Literature summary for 1.14.11.67 extracted from

  • Yang, H.; Mo, H.; Fan, D.; Cao, Y.; Cui, S.; Ma, L.
    Overexpression of a histone H3K4 demethylase, JMJ15, accelerates flowering time in Arabidopsis (2012), Plant Cell Rep., 31, 1297-1308 .
    View publication on PubMed
Search for more literature for 1.14.11.67

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required for activity Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana no activity with [histone H3]-N6,N6-dimethyl-L-lysine4, [histone H3]-N6-methyl-L-lysine4, [histone H3]-N6,N6,N6-trimethyl-L-lysine9, [histone H3]-N6,N6-dimethyl-L-lysine9, [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6-dimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine36 and [histone H3]-N6,N6-dimethyl-L-lysine36 ?
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-
[histone H3]-N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 Arabidopsis thaliana
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 [histone H3]-N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2
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 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana O64752
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-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA affinity column chromatography Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ARTK(me3)QTARKS + 2-oxoglutarate + O2
-
 Arabidopsis thaliana ARTK(me2)QTARKS + succinate + formaldehyde + CO2
-
 ?
additional information no activity with [histone H3]-N6,N6-dimethyl-L-lysine4, [histone H3]-N6-methyl-L-lysine4, [histone H3]-N6,N6,N6-trimethyl-L-lysine9, [histone H3]-N6,N6-dimethyl-L-lysine9, [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6-dimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine36 and [histone H3]-N6,N6-dimethyl-L-lysine36 Arabidopsis thaliana ?
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[histone H3]-N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2
-
 Arabidopsis thaliana [histone H3]-N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2
-
 ?

Subunits

Subunits Comment Organism
? x * 95000, His-tagged enzyme, SDS-PAGE Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
H3K4me3-specific demethylase
-
 Arabidopsis thaliana
JMJ15
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 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function the enzyme is involved in the control of flowering time by demethylating [histone H3]-N6,N6,N6-trimethyl-L-lysine4 at flowering locus C chromatin Arabidopsis thaliana