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Literature summary for 1.14.11.61 extracted from

  • Kai, K.; Mizutani, M.; Kawamura, N.; Yamamoto, R.; Tamai, M.; Yamaguchi, H.; Sakata, K.; Shimizu, B.
    Scopoletin is biosynthesized via ortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase in Arabidopsis thaliana (2008), Plant J., 55, 989-999 .
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.036
-
trans-feruloyl-CoA 30°C, pH 6.5 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana trace reactions with p-coumaroyl CoA, no substrate: ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA, benzoyl CoA ?
-
?
trans-feruloyl-CoA + 2-oxoglutarate + O2 Arabidopsis thaliana
-
trans-6-hydroxyferuloyl-CoA + succinate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9LHN8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information trace reactions with p-coumaroyl CoA, no substrate: ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA, benzoyl CoA Arabidopsis thaliana ?
-
?
trans-feruloyl-CoA + 2-oxoglutarate + O2
-
Arabidopsis thaliana trans-6-hydroxyferuloyl-CoA + succinate + CO2
-
?

Synonyms

Synonyms Comment Organism
feruloyl CoA ortho-hydroxylase 1
-
Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
11
-
trans-feruloyl-CoA 30°C, pH 6.5 Arabidopsis thaliana

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function T-DNA insertion mutants of F6'H1 show severe reductions in scopoletin and scopolin levels in the roots. The pattern of F6'H1 expression is consistent with the patterns of scopoletin and scopolin accumulation Arabidopsis thaliana