Any feedback?
Literature summary for 1.14.11.6 extracted from
- Substitution of nucleoside triphosphates for ascorbate in the thymine 7-hydroxylase reaction of Rhodotorula glutinis (1979), J. Biol. Chem., 254, 26-29.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| (beta,gamma-methylene)adenosine 5'-triphosphate | at 1 mM 2.5fold stimulation of the thymine dependent reaction | Rhodotorula glutinis |  |
| Adenyl-5'-ylimidodiphosphate | at 1 mM 2fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
| ADP | at 1 mM 2.5fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
| ascorbate | at 1 mM 10fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
| ATP | at 1 mM 3.7fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
| GTP | at 1 mM 2fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
| UTP | at 1 mM 2fold stimulation of the thymine dependent reaction | Rhodotorula glutinis | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | - |
Rhodotorula glutinis | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thymine + 2-oxoglutarate + O2 | Rhodotorula glutinis | - |
5-hydroxymethyluracil + succinate + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodotorula glutinis | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rhodotorula glutinis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thymine + 2-oxoglutarate + O2 | - |
Rhodotorula glutinis | 5-hydroxymethyluracil + succinate + CO2 | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 98 | - |
50% activity after 5 min of ascorbate or ATP-dependent stimulation of thymine dependent reaction | Rhodotorula glutinis |
| 98 | - |
20% activity after 15 min of ascorbate or ATP-dependent stimulation of thymine dependent reaction | Rhodotorula glutinis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
