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Literature summary for 1.14.11.33 extracted from

  • Soll, J.M.; Sobol, R.W.; Mosammaparast, N.
    Regulation of DNA alkylation damage repair lessons and therapeutic opportunities (2017), Trends Biochem. Sci., 42, 206-218 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.11.33

Inhibitors

Inhibitors Comment Organism Structure
D-2-hydroxyglutarate
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA-1-methyladenine + 2-oxoglutarate + O2 Homo sapiens
-
 DNA-adenine + formaldehyde + succinate + CO2
-
 ?
DNA-3-methylcytosine + 2-oxoglutarate + O2 Homo sapiens
-
 DNA-cytosine + formaldehyde + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6NS38
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-1-methyladenine + 2-oxoglutarate + O2
-
 Homo sapiens DNA-adenine + formaldehyde + succinate + CO2
-
 ?
DNA-3-methylcytosine + 2-oxoglutarate + O2
-
 Homo sapiens DNA-cytosine + formaldehyde + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
AlkB
-
 Homo sapiens
ALKBH2 isoform Homo sapiens