Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.11.17 extracted from

  • Luo, L.; Pappalardi, M.B.; Tummino, P.J.; Copeland, R.A.; Fraser, M.E.; Grzyska, P.K.; Hausinger, R.P.
    An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation (2006), Anal. Biochem., 353, 69-74.
    View publication on PubMed
Search for more literature for 1.14.11.17

Protein Variants

Protein Variants Comment Organism
W98I reduced activity compared to the wild type enzyme Escherichia coli
Y73I reduced activity compared to the wild type enzyme Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.009
-
 2-oxoglutarate wild type enzyme, in the presence of taurine Escherichia coli
0.012
-
 2-oxoglutarate mutant enzyme Y73I, in the presence of taurine Escherichia coli
0.015
-
 2-oxoglutarate mutant enzyme Y73I, without taurine Escherichia coli
0.02
-
 2-oxoglutarate wild type enzyme, without taurine Escherichia coli
0.048
-
 2-oxoglutarate mutant enzyme W98I, in the presence of taurine Escherichia coli
0.052
-
 taurine wild type enzyme Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
taurine + 2-oxoglutarate + O2
-
 Escherichia coli sulfite + aminoacetaldehyde + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
Fe(II)/2-oxoglutarate-dependent taurine dioxygenase
-
 Escherichia coli
taurine (2-aminoethanesulfonate)/2-oxoglutarate dioxygenase
-
 Escherichia coli
taurine/2-oxoglutarate dioxygenase
-
 Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.06
-
 2-oxoglutarate wild type enzyme, without taurine Escherichia coli
0.12
-
 2-oxoglutarate mutant enzyme Y73I, without taurine Escherichia coli
0.14
-
 2-oxoglutarate mutant enzyme W98I, in the presence of taurine Escherichia coli
1
-
 2-oxoglutarate mutant enzyme Y73I, in the presence of taurine Escherichia coli
3
-
 2-oxoglutarate wild type enzyme, in the presence of taurine Escherichia coli
3
-
 taurine wild type enzyme Escherichia coli