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Literature summary for 1.14.11.16 extracted from

  • Huyan, T.; Li, Q.; Ye, L.J.; Yang, H.; Xue, X.P.; Zhang, M.J.; Huang, Q.S.; Yin, D.C.; Shang, P.
    Inhibition of human natural killer cell functional activity by human aspartyl alpha-hydroxylase (2014), Int. Immunopharmacol., 23, 452-459 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Homo sapiens 5783
-
plasma membrane
-
Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q12797
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocytoma cell the enzyme is overexpressed in many malignant neoplasms Homo sapiens
-
serum the enzyme can be detected from the sera of tumor patients Homo sapiens
-

Synonyms

Synonyms Comment Organism
aspartyl beta-hydroxylase
-
Homo sapiens
HAAH
-
Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme is involved in regulating tumor cell infiltration and metastasis in tumor patients with malignant neoplasms. One of the ways by which the enzyme actively promotes tumor formation and proliferation is by inhibiting natural killer cell-surveillance activity Homo sapiens