Literature summary for 1.14.11.13 extracted from

Otani, M.; Yoon, J.M.; Park, S.H.; Asami, T.; Nakajima, M.
Screening and characterization of an inhibitory chemical specific to Arabidopsis gibberellin 2-oxidases (2010), Bioorg. Med. Chem. Lett., 20, 4259-4262.

Search for more literature for 1.14.11.13

Inhibitors

Inhibitors	Comment	Organism	Structure
methyl 6-chloro-3H-1,2,3-benzodithiazole-4-carboxylate 2-oxide	highly specific inhibitor of gibberellin 2-oxidase, evaluation as inhibitor of gibberellin catabolism in planta. The compound promotes both the germination and elongation of Arabidopsis seedlings	Arabidopsis thaliana
additional information	inhibitor development block GA catabolism in plants, in vitro random screening, overview. No or poor inhibition by 2-acetamido-5-chlorobenzoic acid methylester, 5-chlorooxindole, 6-chloro-2-mercaptobenzothiazole, 7-chloro-2H-1,4-benzothiazin-3(4H)-one, methyl 5-chloroanthranilate, methyl 5-chloro-2-nitrobenzoate, methyl 3-chlorobenzoate	Arabidopsis thaliana
prohexadione	inhibits gibberellin 2-oxidase, but is not effective in promoting germination and elongation of Arabidopsis seedlings	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
seedling	-	Arabidopsis thaliana	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
16,17-dihydrogibberellin 4 + 2-oxoglutarate + O2	-	Arabidopsis thaliana	16,17-dihydrogibberellin 34 + succinate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
gibberellin 2-oxidase	-	Arabidopsis thaliana

General Information

General Information	Comment	Organism
metabolism	the enzyme is involved in the biosynthesis of gibberellin in higher plants, overview	Arabidopsis thaliana
physiological function	hydroxylation of gibberellin at the 2-position causes the inactivation of plant hormones gibberellins	Arabidopsis thaliana

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Release 2023.1 (January 2023)