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Literature summary for 1.14.11.1 extracted from

  • Garcia-Delgado, M.; Peral, M.J.; Duran, J.M.; Garcia-Miranda, P.; Calonge, M.L.; Ilundain, A.A.
    Ontogeny of Na(+)/L-carnitine transporter and of gamma-trimethylaminobutyraldehyde dehydrogenase and gamma-butyrobetaine hydroxylase genes expression in rat kidney (2009), Mech. Ageing Dev., 130, 227-233.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus enzyme is involved in L-carnitine (3-hydroxy-4-N-trimethylaminobutyrate) biosynthesis ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9QZU7 foetuses, newborn, suckling, weaning and adult rats
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Rattus norvegicus Q9QZU7 male Wister rat
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Source Tissue

Source Tissue Comment Organism Textmining
kidney
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 Rattus norvegicus
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liver
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 Rattus norvegicus
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renal cortex
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 Rattus norvegicus
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renal medulla
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 Rattus norvegicus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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 BBH mRNA is detected during the suckling period onwards and its abundance is not changed significantly by maturation, expression of BBH mRNA is undetectable in foetuses and newborn rats, it is measurable in suckling rats, no significant differences are observed between cortical and medullar BBH mRNA levels Rattus norvegicus
additional information
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 levels of liver mRNA BBH are approx. 650times and 2times greater than the maximal values measured in kidneys Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is involved in L-carnitine (3-hydroxy-4-N-trimethylaminobutyrate) biosynthesis Rattus norvegicus ?
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 ?

Synonyms

Synonyms Comment Organism
BBH
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 Rattus norvegicus
gamma-butyrobetaine hydroxylase
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 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus detection of mRNA levels during suckling period onwards, expression is ontogenically regulated up