Any feedback?
Literature summary for 1.13.99.1 extracted from
- Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism (2006), Proc. Natl. Acad. Sci. USA, 103, 15032-15037.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| L-cysteine | 2 mM | Mus musculus |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Mus musculus |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystals grow from a solution containing 20 mg/ml MIOX, 20 mM myo-inositol, 50 mM Mes pH 6.0, 50 mM NaCl, 2 mM Tris(2-carboxyethyl)-phosphine hydrochloride and 4.4 M sodium formate | Mus musculus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | 1 mM | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni2+-affinity chromatography | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-chiro-inositol + O2 | - |
Mus musculus | ? | - |
? | |
| myo-inositol + O2 | - |
Mus musculus | D-glucuronate + H2O | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | x-ray crystallography | Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MIOX | - |
Mus musculus |
| Myo-inositol oxygenase | - |
Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
