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Literature summary for 1.13.99.1 extracted from

  • Xing, G.; Barr, E.W.; Diao, Y.; Hoffart, L.M.; Prabhu, K.S.; Arner, R.J.; Reddy, C.C.; Krebs, C.; Bollinger, J.M.
    Oxygen activation by a mixed-valent, diiron(II/III) cluster in the glycol cleavage reaction catalyzed by myo-inositol oxygenase (2006), Biochemistry, 45, 5402-5412.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
L-cysteine
-
Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli in the presence of the iron chelator, 1,10-phenanthroline to create iron-free MIOX Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Iron contains a non-heme dinuclear iron cluster, observations implicate the mixed-valent, diiron-(II/III) form of the enzyme as the active state Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
AG1-X8 resin column chromatography Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myo-inositol + O2
-
Mus musculus D-glucuronate + H2O
-
?

Synonyms

Synonyms Comment Organism
MIOX
-
Mus musculus
Myo-inositol oxygenase
-
Mus musculus