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Literature summary for 1.13.12.7 extracted from

  • Matsuki, H.; Suzuki, A.; Kamaya, H.; Ueda, I.
    Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanate (1999), Biochim. Biophys. Acta, 1426, 143-150.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
butanoic acid IC50: 13.6 mM Photinus pyralis
Decanoic acid IC50: 0.0132 mM Photinus pyralis
dodecanoic acid IC50: 0.0012 mM Photinus pyralis
hexadecanoic acid IC50: 0.00067 mM Photinus pyralis
hexanoic acid IC50: 3.4 mM Photinus pyralis
octadecanoic acid IC50: 0.00063 mM Photinus pyralis
octanoic acid IC50: 2.9 mM Photinus pyralis
tetradecanoic acid IC50: 0.00068 mM Photinus pyralis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
luciferin + O2 + ATP Photinus pyralis
-
oxyluciferin + AMP + diphosphate + CO2 + light
-
ir

Organism

Organism UniProt Comment Textmining
Photinus pyralis
-
firefly
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
luciferin + O2 + ATP
-
Photinus pyralis oxyluciferin + AMP + diphosphate + CO2 + light
-
ir

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00063
-
IC50: 0.00063 mM Photinus pyralis octadecanoic acid
0.00067
-
IC50: 0.00067 mM Photinus pyralis hexadecanoic acid
0.00068
-
IC50: 0.00068 mM Photinus pyralis tetradecanoic acid
0.0012
-
IC50: 0.0012 mM Photinus pyralis dodecanoic acid
0.0132
-
IC50: 0.0132 mM Photinus pyralis Decanoic acid
2.9
-
IC50: 2.9 mM Photinus pyralis octanoic acid
3.4
-
IC50: 3.4 mM Photinus pyralis hexanoic acid
13.6
-
IC50: 13.6 mM Photinus pyralis butanoic acid