Protein Variants | Comment | Organism |
---|---|---|
N18A | the mutation suppresses the kcat value 120fold compared to the wild type enzyme | Streptomyces nogalater |
N63A | the mutation suppresses the kcat value 50fold compared to the wild type enzyme | Streptomyces nogalater |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bisanthrone | - |
Streptomyces nogalater | |
dithranone | - |
Streptomyces nogalater |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1 | - |
dithranol | at pH 9.8 and 20°C | Streptomyces nogalater | |
0.22 | - |
dithranol | at pH 6.3 and 20°C | Streptomyces nogalater | |
0.41 | - |
O2 | at pH 9.8 and 20°C | Streptomyces nogalater | |
0.43 | - |
O2 | at pH 6.3 and 20°C | Streptomyces nogalater |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynogalonate + O2 | Streptomyces nogalater | - |
nogalonate + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces nogalater | O54259 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynogalonate + O2 | - |
Streptomyces nogalater | nogalonate + H2O | - |
? | |
dithranol + O2 | - |
Streptomyces nogalater | dithranolate + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 16980, calculated from amino acid sequence | Streptomyces nogalater |
Synonyms | Comment | Organism |
---|---|---|
SnoaB | - |
Streptomyces nogalater |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
O2 | at pH 6.3 and 20°C | Streptomyces nogalater | |
0.17 | - |
dithranol | at pH 6.3 and 20°C | Streptomyces nogalater | |
1 | - |
dithranol | at pH 9.8 and 20°C | Streptomyces nogalater | |
1.83 | - |
O2 | at pH 9.8 and 20°C | Streptomyces nogalater |
General Information | Comment | Organism |
---|---|---|
physiological function | involved in nogalamycin biosynthesis | Streptomyces nogalater |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | - |
dithranol | at pH 6.3 and 20°C | Streptomyces nogalater | |
0.83 | - |
dithranol | at pH 6.3 and 20°C | Streptomyces nogalater | |
4.3 | - |
dithranol | at pH 9.8 and 20°C | Streptomyces nogalater | |
9.7 | - |
dithranol | at pH 9.8 and 20°C | Streptomyces nogalater |