Activating Compound | Comment | Organism | Structure |
---|---|---|---|
4-Methyllysine | at low substrate concentrations | Pseudomonas fluorescens | |
5-Methyllysine | at low substrate concentrations | Pseudomonas fluorescens | |
Nepsilon-Methyllysine | at low substrate concentrations | Pseudomonas fluorescens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-Methyllysine | at higher substrate concentrations, competitive inhibitor | Pseudomonas fluorescens | |
5-Methyllysine | at higher substrate concentrations, competitive inhibitor | Pseudomonas fluorescens | |
Nepsilon-Methyllysine | at higher substrate concentrations, competitive inhibitor | Pseudomonas fluorescens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Pseudomonas fluorescens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | metals play no role in lysine monooxygenase | Pseudomonas fluorescens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas fluorescens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-chlorolysine + O2 | oxidase activity | Pseudomonas fluorescens | ? | - |
? | |
4-methyllysine + O2 | oxidase activity | Pseudomonas fluorescens | 2-keto-4-methyl-6-amino-n-hexanoate + NH3 + H2O2 | - |
? | |
5-hydroxylysine + O2 | oxidase activity | Pseudomonas fluorescens | ? | - |
? | |
5-methyllysine + O2 | monooxygenase activity | Pseudomonas fluorescens | 4-methyl-5-aminopentanamide + CO2 + H2O | - |
? | |
L-homoarginine + O2 | - |
Pseudomonas fluorescens | ? | - |
? | |
L-lysine + O2 | monooxygenase activity | Pseudomonas fluorescens | 5-aminopentanamide + CO2 + H2O | - |
? | |
additional information | analogs with a modified carboxyl or alpha-amino group are inactive as substrates | Pseudomonas fluorescens | ? | - |
? | |
additional information | L-lysine analogs with a chloro or hydroxyl group at either the delta or the gamma position are both oxygenated and oxidized | Pseudomonas fluorescens | ? | - |
? | |
Nepsilon-methyllysine + O2 | monooxygenase activity | Pseudomonas fluorescens | 5-methylaminopentanamide + CO2 + H2O | - |
? | |
threo-4-hydroxy-L-lysine + O2 | oxidase activity | Pseudomonas fluorescens | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
34 | - |
assay at | Pseudomonas fluorescens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | contains 2 mol of FAD per mol of enzyme | Pseudomonas fluorescens |