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Literature summary for 1.13.12.1 extracted from

  • Flashner, M.S.; Massey, V.
    Flavoprotein oxygenases (1974), Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York, , 245-283.
No PubMed abstract available
Search for more literature for 1.13.12.1

General Stability

General Stability Organism
dithionite and thioglycolate protect against inactivation by O2 Streptomyces griseus
L-arginine protects against inactivation by O2 Streptomyces griseus
storage in N2-atmosphere protects against inactivation by O2 Streptomyces griseus

Inhibitors

Inhibitors Comment Organism Structure
diethyldicarbonate modifies one histidyl residue per flavin Streptomyces griseus
homoarginine competitive to L-arginine Streptomyces griseus

Organism

Organism UniProt Comment Textmining
Streptomyces griseus
-
-
-

Oxidation Stability

Oxidation Stability Organism
partially purified enzyme extremely unstable in presence of O2 Streptomyces griseus

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
 Streptomyces griseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
canavanine + O2 i.e. 2-amino-4-(guanidinooxy)butyrate, poor substrate Streptomyces griseus 3-guanidoxypropionamide + CO2 + H2O
-
 ?
homoarginine + O2
-
 Streptomyces griseus 5-guanidinovaleramide + CO2 + H2O
-
 ?
L-arginine + O2
-
 Streptomyces griseus 4-guanidinobutanamide + CO2 + H2O
-
 ?
additional information no activity with L-lysine Streptomyces griseus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.1
-
 canavanine Streptomyces griseus
8
-
 homoarginine Streptomyces griseus
9
-
 L-arginine Streptomyces griseus

Cofactor

Cofactor Comment Organism Structure
flavin flavoprotein Streptomyces griseus