Literature summary for 1.13.11.63 extracted from

Jlali, M.; Graulet, B.; Chauveau-Duriot, B.; Godet, E.; Praud, C.; Nunes, C.S.; Le Bihan-Duval, E.; Berri, C.; Duclos, M.J.
Nutrigenetics of carotenoid metabolism in the chicken a polymorphism at the beta,beta-carotene 15,15'-mono-oxygenase 1 (BCMO1) locus affects the response to dietary beta-carotene (2014), Br. J. Nutr., 111, 2079-2088 .

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Cloned(Commentary)

Cloned (Comment)	Organism
DNA and amino acid sequence determination and analysis, genotyping, two fully linked SNPs are identified within the proximal promoter of the BCMO1 gene at -678 and -621 upstream from the ATG codon corresponding to the substitution of two adenines (A/A) by two guanines (G/G) and defined two haplotypes, AN57A and GN57G, which segregate within chicken lines, quantitative PCR enzyme expression analysis	Gallus gallus

Cloned (Comment)

Organism

DNA and amino acid sequence determination and analysis, genotyping, two fully linked SNPs are identified within the proximal promoter of the BCMO1 gene at -678 and -621 upstream from the ATG codon corresponding to the substitution of two adenines (A/A) by two guanines (G/G) and defined two haplotypes, AN57A and GN57G, which segregate within chicken lines, quantitative PCR enzyme expression analysis

Gallus gallus

Protein Variants

Protein Variants	Comment	Organism
additional information	genotyping, identification of two genotypes	Gallus gallus

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
duodenum	-	Gallus gallus	-
liver	-	Gallus gallus	-
muscle	pectoralis major	Gallus gallus	-

Synonyms

Synonyms	Comment	Organism
Bcmo1	-	Gallus gallus
beta,beta-carotene 15,15'-mono-oxygenase 1	-	Gallus gallus

Expression

Organism	Comment	Expression
Gallus gallus	addition of beta-carotene to the diet reduces the mRNA levels of BCMO1 in the liver in both genotypes, haplotypes AN57A and GN57G	down

General Information

General Information	Comment	Organism
malfunction	a polymorphism at the beta,beta-carotene 15,15'-monooxygenase 1 (BCMO1) locus affects the response to dietary beta-carotene. Vitamin A and vitamin E status are affected by genotype or the incorporation of beta-carotene in the diet, but the effects varies according to the tissue, phenotypes, overview	Gallus gallus
physiological function	enzyme BCMO1 is responsible for the symmetrical cleavage of beta-carotene into retinal	Gallus gallus