Application | Comment | Organism |
---|---|---|
synthesis | stepwise cleavage by BCO2, i.e. beta-carotene-9',10'-oxygenase, and BCO1 with beta-apo-10'-carotenol as an intermediate can provide a mechanism to tailor asymmetric carotenoids such as beta-cryptoxanthin for vitamin A production | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | subjection of wild type, Bco1-/-, Bco2-/-, and Bco1-/-/Bco2-/- double knock-out mice to a controlled diet providing beta-carotene as the sole source for apocarotenoid production | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-apo-10'-carotenol + O2 | Mus musculus | beta-apo-10'-carotenol is the major long-chain beta-apocarotenoid in mouse liver | ? | - |
? | |
beta-carotene + O2 | Mus musculus | - |
2 all-trans-retinal | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9JJS6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-apo-10'-carotenol + O2 | beta-apo-10'-carotenol is the major long-chain beta-apocarotenoid in mouse liver | Mus musculus | ? | - |
? | |
beta-carotene + O2 | - |
Mus musculus | 2 all-trans-retinal | - |
? | |
additional information | symmetric cleavage by BCO1 yields retinoids, i.e. beta-15'-apocarotenoids, C20 | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BCO1 | - |
Mus musculus |
beta-carotene-15,15'-oxygenase | - |
Mus musculus |