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Literature summary for 1.13.11.54 extracted from

  • Chang, M.L.; Huang, Y.H.; Cheng, J.C.; Yeh, C.T.
    Interaction between hepatic membrane type 1 matrix metalloproteinase and acireductone dioxygenase 1 regulates hepatitis C virus infection (2016), J. Viral Hepat., 23, 256-266 .
    View publication on PubMed

Application

Application Comment Organism
medicine matrix metalloproteinase MT1-MMP physically interacts with claudin-1 and acireductone dioxygenase 1, both associated with hepatitis C virus cell entry. Positive cytoplasmic ADI1 in liver biopsies is associated with higher serum hepatitis C virus RNA levels. Positive MT1-MMP and ADI1 interaction is associated with lower tissue hepatitis C virus RNA levels. Hepatic hepatitis C virus RNA levels are positively associated with ADI1 levels in the MT1-MMP and ADI1 coimmunoprecipitates Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BV57
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
ADI1
-
Homo sapiens

General Information

General Information Comment Organism
physiological function matrix metalloproteinase MT1-MMP physically interacts with claudin-1 and acireductone dioxygenase 1, both associated with hepatitis C virus cell entry Homo sapiens