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Literature summary for 1.13.11.52 extracted from
- Indoleamine 2,3-dioxygenase protects corneal endothelial cells from UV mediated damage (2006), Exp. Eye Res., 82, 416-426.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P28776 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| corneal epithelium | consistently expresses the enzyme at low levels. Exposure to UV-light leads to a dose-responding upregulation. Overexpression of indoleamine-pyrrole 2,3-dioxygenase could reduce apoptosis significantly following UV-B irradiation | Mus musculus | - |
| dendritic cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + O2 | - |
Mus musculus | N-formyl-L-kynurenine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IDO | - |
Mus musculus |
| Indoleamine-pyrrole 2,3-dioxygenase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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